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KMID : 0882420150880010094
Korean Journal of Medicine
2015 Volume.88 No. 1 p.94 ~ p.100
Four Cases of Acquired Aplastic Anemia Affecting an Entire Family after Ingesting Ganoderma lucidum
Jung Joo-Hyuk

Lee Hyun-Woo
Lee Yoo-Jin
Lee Hye-Ran
Um Tae-Hyun
Park Ji-Yeon
Yi Seong-Yoon
Abstract
We report four cases of Ganoderma lucidum-induced aplastic anemia involving members of the same family. A 33-year-old man and three family members were admitted to the hospital due to fever and pancytopenia. The illness arose after ingesting herbal wine containing G. lucidum 2 weeks earlier. A bone-marrow biopsy showed hypocellularity in three of the four family members (the exception was the one who died). They were treated with supportive management, including transfusions, granulocyte colony stimulating factor, and empirical antibiotics for neutropenic fever. The pancytopenia improved 4?5 weeks after the symptoms first appeared.
KEYWORD
Aplastic anemia, Medicinal plants, Ganoderma lucidum
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